Chronic Liver Disease and Thrombocytopenia: Symptoms, Causes & Treatment

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The Liver is one of the most important organs of the human body. It regulates metabolism, detoxification, digestion, storage as well as immune function.Any disease or infection of this organ lead to discomfort in day to day life.  

Understanding Chronic Liver Disease

Chronic Liver Disease is a progressive and persistent long term damage to the liver lasting for about 6 months and more.It leads to inflammation and scarring of liver tissue. Hepatitis B infection, Alcohol addiction, liver diseases are the major causes of Chronic Liver Disease.

What Is Chronic Refractory Thrombocytopenia?

Chronic Refractory Thrombocytopenia refers to persistently low count of platelets. It is also known as refractory immune thrombocytopenia. Autoimmune destruction, HIV, Liver Diseases are the major causes of Chronic Refractory Thrombocytopenia

How Liver Disease Causes Low Platelet Count?

Following are the 3 major ways in which liver disease causes low platelet count:

  • Liver is responsible for thrombopoetin hormone production that stimulate platelet production. Therefore, when the liver damage begins, it leads to low platelet production.

  • Chronic Liver Disease leads to hypertension that cause spleen enlargement.Thus, spleen destroy its own immune cells.  

  • Bone Marrow suppression due to alcohol intoxication, disease etc can also lead to decrease in platelet production.

 Common Symptoms & Risk Factors

Following are the common symptoms of Chronic Liver Disease and Chronic Refractory Thrombocytopenia:

  • Bruising

  • Bleeding Gums and Nose

  • Blood in Urine

  • Fatigue

  • Internal Bleeding

  • Heavy Menstrual Period

 Available Treatment Approaches

Following are the different treatment approaches for these diseases:

  • Splenectomy: Removal of enlarged spleen via operation.

  • Immunosupressive Therapies: To reduce immune mediated destruction of blood cells.

  • Treatment of Cause: Medication or other therapies to treat the cause such as treatment of hepatitis B.

  • Thrombopoietin Receptor Agonists: Doctor Prescribe Doptelet 20mg Tablet for Platelet production. It contains avatrombopag that boost Thrombopoietin production. As a result, platelet production increases.

 Conclusion

To conclude, Chronic Liver Disease is a long-term condition leading to liver inflammation and scarring, often caused by Hepatitis B, alcohol addiction, and other liver diseases. It can result in Chronic Refractory Thrombocytopenia, characterized by persistently low platelet counts due to factors such as reduced thrombopoietin production from liver damage, spleen enlargement causing immune cell destruction, and bone marrow suppression. Common symptoms include bruising, bleeding gums, fatigue, and heavy menstrual periods. Treatment options encompass splenectomy, immunosuppressive therapies, addressing underlying causes, and the use of thrombopoietin receptor agonists for increasing platelet production.To get great offers on Doptelet 20mg Tablet Price, visit Globans Pharma now.

 FAQs

1. What are the side effects of Doptelet 20mg Tablet?

The side effects of this medication are diziness, headache, nausea, weakness etc.

2. Is chronic Liver Disease Fatal?

Yes, it can be fatal if not treated timely with effective medication.

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